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Deborah Fraser, PhD

Institution: 
Department: 
Accepting Applicants: 
Yes
Research Fields, Techniques & Topics: 
Ongoing Projects: 

Investigate the role of innate immune protein C1q in atherosclerosis:

in vitro studies on C1q modulation of macrophage gene expression during ingestion of damaged lipoproteins

in vitro studies on C1q modulation of macrophage functions (survival, inflammation, phagocytosis) during ingestion of damaged lipoproteins

in vitro studies on C1q modulation of the macrophage lipidome

in vitro studies in the regulation of signal pathways by intracellular C1q

in vitro studies in the expression of complement molecules by macrophages

in vivo studies in mouse models of atherosclerosis

 

Office: Molecular & Life Sciences Center Building, Room 224