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Cayuse: Electronic Submission and Clearance

Important Notice: Cayuse works best and most reliably with Mozilla Firefox. Use of other browsers is not recommended. For Mac users download Mozilla Firefox and open a fresh browser window to begin.


Cayuse 424 is a server-to-server, web-based Pre-Award Grant Proposal Preparation Software package. It allows users to prepare, validate and submit federal grant proposals. Cayuse is also used to streamline and execute the Internal Clearance Routing process. You must be a registerd user to access Cayuse.

Cayuse Provides:

  • Internal Routing for Clearance
  • Simultaneous proposal review
  • Centralized proposal development
  • Grant Submission
  • Tracking
  • Validating
  • Archiving


Cayuse Access and Problem Solving

To request access or resolve problems, please contact our Pre-Award Personnel.


Cayuse Training

Who should receive training

Cayuse training is available for CSULB faculty, administrators and staff involved in research administration, especially the pre-award application process. Please contact your college's assigned Pre-Award Specialist for training.


Frequently Asked Questions About Cayuse

What is Cayuse?

Cayuse is a web-based software tool for pre-award grant proposal preparation, processing, submission, and administration.

Why should CSULB use Cayuse?

Cayuse is intuitive and easy to use. It streamlines the Internal Clearance Form routing process. 

What will Cayuse do for me?

Cayuse offers accuracy, efficiency, and speed of proposal development:

  • PIs can download funding opportunities directly from
  • Cayuse manages institutional information in one location, and applies it consistently to every proposal.
  • Cayuse checks for errors and warnings.
  • Cayuse provides electronic routing.
  • Users can view, edit, and collaborate on proposals in any stage of development.

I’m one of the signatories in the internal clearance routing chain, how can I use Cayuse to review and approve the grant application package submitted by faculty?

As one of the signatories, you will need to log into Cayuse to review the proposal application package, approve it, and submit it to the next signatory. The proposal routing for internal clearance will be automatically handled in Cayuse.

If I go on vacation can I designate someone in my absence to approve a routing?

Yes! Under the People tab, find your designee’s professional profile. Open the profile and on the bottom left click Routing Profile - click the green plus sign to add your delegates. You can leave them on always or you can remove them upon your return.