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Courses - BME Upper Division

300. Bioinformatics and Genomics (3)

Prerequisites: BME 210 and (BIOL 200 or BIOL 212)
Development and application of computational approaches to problems in Biology and Genomics, with focus on formulating interdisciplinary problems as computational problems and then solving these problems using algorithmic techniques. Computational techniques include those from statistics and computer science.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours)

304. Biomedical Signal Processing (3)

Prerequisite: BME 210
Introduction of basic Biomedical Signal Processing Techniques, Z-Transform, Frequency Domain Analysis, Digital Filters, Stability, Event Detection, Temporal and Spectral Feature Extraction.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours)

311. Biomechanics II (3)

Prerequisites: BME 211, MATH 249
Introduction to dynamics, kinematics of particles, Newton’s 2nd law, systems of particles, kinematics of rigid bodies and motion in three dimensions with application to biological systems.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours)

320. Data Acquisition and Analysis (4)

Prerequisite: BME 210. Corequisite: (BIOL 207 or BIOL 342 or BIOL 345)
Introduction to invasive and noninvasive methods of physiological data collection with an emphasis on real time acquisition and processing. Topics include conversion of ionic current to electric current, Nernst Equation, sensors, transducers. Collection and analysis of physiological signals.
Letter grade only (A-F). (Lecture 3 hours, Laboratory 3 hours).

350. Computational Physiology (3)

Prerequisites: (BIOL 207 or BIOL 342 or BIOL 345) and BME 304 and BME 320
Introduction to computational methods and machine learning techniques to analyze cardiovascular and cerebrovascular systems and signals and detect/predict a physiological event of interest. Parametric and non-parametric classification. Hidden Markov models. Clustering. Entropy.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours)

360. Biomedical Instrumentation (4)

Prerequisite: BME 320
Circuit Analysis Methods. Diodes, Transistors, Operational Amplifiers, Differential Amplifiers, Active Filters -- their design principles and applications in Biomedical Instrumentation and Measurement Systems.
Letter grade only (A-F). (Lecture 3 hours, Laboratory 3 hours).

370. Bio-Fluids and Transport (3)

Prerequisites: MATH 249, PHYS 151, (BIOL 200 or BIOL 212), (BIOL 207 or BIOL 342 or BIOL 345) .
Review of basic fluid mechanics concepts, cardiovascular structure, pulmonary anatomy, physiology, respiration, hematology and blood rheology, characteristics of blood vessels, mechanics of heart valves, pulsatile flow, flow and pressure measurement and experiments, flow modeling.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours)

406. Selected Topics in Biomedical Engineering (3)

Prerequisite: Senior standing in the Biomedical Engineering Major.
Each offering is based upon an area of biomedical engineering in which recent advances have been made.
May be repeated to a maximum of 6 units with different topics in different semesters. Topics announced in the Schedule of Classes. Letter grade only (A-F). (Lecture 2 hours, laboratory 3 hours)

410. Biomedical Image Processing (3)

Prerequisite: BME 350 with a grade of “C” or better.
Principles of imaging modalities in radiology: X-ray, Computed Tomography, Ultrasound imaging, and Magnetic Resonance Imaging. Principles of wave propagation, transmission, reflection, refraction, attenuation, absorption, scattering, acoustic impedance. Ultrasound transducers. Principles of light. Specific application in Mammography and angiography.
Letter grade only (A-F). (Lecture 2 hours, laboratory 3 hours)

420. Biomaterials (3)

Prerequisites: BME 311, CHEM 111B, BIOL 200 or BIOL 212 or equivalent with a grade of “C” or better.
Overview of natural and synthetic materials for biomedical applications, including metals, ceramics and polymers. Mechanical, electrical, chemical, and surface characterization of biomaterials. Design of hard and soft tissue implant materials. Biocompatibility of materials, wound repair, medical devices and government regulations.
Letter grade only (A-F). (Lecture 2 hours, laboratory 3 hours)

430. Neurocritical Care (3)

Prerequisite: BME 350 with a grade of “C” or better.
Recent techniques for the analysis of healthy and pathological structure and function of the neurological system.
Letter grade only (A-F). (Lecture 3 hours)

440. Healthcare Informatics (3)

Prerequisite: BME 300 with a grade of “C” or better.
Principles of Healthcare Informatics. Digital Imaging and Communication in Medicine (DICOM) standard. Medical Imaging. Networking. Teleradiology and Telemedicine. Scaling clinical projects. Security, Confidentiality, Availability. Fault Tolerance and Robustness. Clinical Modeling and Performance Optimization. Clinical decision support. HL7, IHE standards.
Letter grade only (A-F). (Lecture 2 hours, Laboratory 3 hours).

445. Biological Databases (3)

Prerequisite: BME 440 with a grade of “C” or better.
Efficient organization of biological data. Object oriented databases, data modeling and description. Survey of current biological databases. Implementation of a database focused on a biological topic. Letter grade only (A-F).
(Lecture 2 hours, Laboratory 3 hours).

450. Stem Cell and Tissue Engineering (3)

Prerequisites: BME 420, BIOL 200 or BIOL 212 all with a grade of “C” or better.
Stem cell biology and recent engineering techniques to use stem cells for biomedical engineering purposes and their microenvironment. Letter grade only (A-F).
(Lecture 2 hours, Laboratory 3 hours).

490A. Biomedical Engineering Capstone (3)

Prerequisites: Senior standing and BME 370 with a grade of “C” or better.
Design of a biomedically-oriented hardware or software project(s) including related instrument/device or signal or image processing concepts. Associated constraints, standards, reliability, and verification issues. Individual and group projects.
Letter grade only (A-F). (Lecture 2 hours, laboratory 3 hours)

490B. Biomedical Engineering Capstone (3)

Prerequisite: BME 490A with a grade of “C” or better.
Implementation of a biomedically-oriented hardware or software project(s) including related instrument/device or signal or image processing concepts. Associated constraints, standards, reliability, and verification issues. Individual and group projects.
Letter grade only (A-F). (Lecture 2 hours, laboratory 3 hours)


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