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Courses - CHEM Graduate Level

521./421. Physical Organic Chemistry (3) F

Prerequisites: CHEM 220B with a grade of "C" or better.
Prerequisite/Corequisite: CHEM 371B or CHEM 377B.
Undergraduates enroll in CHEM 421; graduates in CHEM 521.
Theoretical interpretation of chemical and physical properties of organic compounds: mathematical derivations of rate equations from experimental results, quantitative comparison of organics compounds reactivities, mathematical correlations of structure and properties. Solving problems relating to reaction mechanisms to described factors.
Letter grade only (A-F). (Lecture 3 hrs.)

522. Selected Topics in Organic Chemistry (3)

Prerequisite: CHEM 421 or CHEM 521 or consent of instructor.
Areas of current interest in organic chemistry.
Letter grade only (A-F). May be repeated to a maximum of 6 units with different topics. Topics announced in the Schedule of Classes. (Lecture 3 hrs.)

523. Synthetic Methods (3)

Prerequisites: CHEM 220B with a grade of "C" or better; CHEM 521 recommended
Introduction to current methods of synthetic transformations; topics may include, but not limited to the following: Retrosynthetic analysis, protecting groups, functional group transformations, enolate chemistry, organometallics, stereochemistry and conformational analysis, pericyclic reactions, alkene functionalization and reactions of carbon nucleophiles.
Letter grade only (A-F). (Lecture 3 hrs.)

524. Catalysis in Organic Chemistry (3)

A study of catalysis beginning with a general theory of catalysis. The course also covers catalysis in synthetic organic chemistry centered on metals and ligated metals and catalysis centered on organic molecules as the catalytic species.
Letter grade only (A-F). (Lecture 3 hrs.)

525. Introduction to Supramolecular Chemistry (3)

Prerequisites: Proficiency in any of the following as demonstrated by ACS placement exam: Organic, Biochemistry or Inorganic
Introduction to non-covalent interactions will be presented in the context of molecular recognition and self-assembly. Synthetic and biological examples will be used to understand these principles and how they can be applied to the preparation of new materials.
Letter grade only (A-F). (Lecture 3 hrs.)

531. Advances in Inorganic Chemistry (3)

Prerequisite: CHEM 431 or consent of instructor.
Current topics and advances in inorganic chemistry.
May be repeated to a maximum of 6 units with different topics. Letter grade only (A-F). (Lecture 3 hrs.)

532. Inorganic Materials Chemistry (3)

Prerequisite: CHEM 431 or consent of instructor.
Advanced studies in bonding in solids, crystal structure variations, band theory and electronic structure, crystal structure-electronic structure-physical properties relationship, electron transport properties, magnetic materials, materials by design for technological aplications.
Letter grade only (A-F). (Lecture 3 hrs.)

533. Physical Techniques in Inorganic Chemistry (3)

Prerequisite: CHEM 431 or consent of instructor.
An introduction to physical techniques commonly used in inorganic chemistry with focus on the magnetic resonance spectroscopic techniques: EPR and multinuclear NMR.
Letter grade only (A-F). (Lecture 3 hrs.)

534. Crystal Structure Analysis (3)

Prerequisite: CHEM 431 or consent of instructor.
An introduction to structural methods commonly used in inorganic chemistry with focus on single crystal and powder X-ray diffraction.
Letter grade only (A-F). (Lecture 3 hrs.)

541. Biochemistry Core for Graduate Study (3)

Prerequisites: CHEM 441A,B
The course is divided into three topics: (i) structure and evolution of proteins and their complexes with nucleic acids, lipids and carbohydrates, including structure determination methods; (ii) metabolic regulation from mechanistic and physiological viewpoints; (iii) applications of biochemical methodologies.
Letter grade only (A-F), (Lecture 3 hrs.)

542. Selected Topics in Biochemistry (3)

Prerequisites: CHEM 441B and CHEM 541 all with a grade of "C" or better; or consent of instructor.
Intensive discussion of a limited aspect of biochemistry with reference to current literature. Course content will vary from year to year.
May be repeated to a maximum of 6 units with different topics in different semesters. Topics announced in the Schedule of Classes. (Lecture 3 hrs.) Letter grade only (A-F).

544. Physical Biochemistry (3)

Prerequisites: Either CHEM 371A,B or CHEM 377A,B; CHEM 441B; CHEM 541 all with the grade of "C" or better; or consent of instructor.
Physical chemical aspects of protein and nucleic acid chemistry and related analytical methods.
Letter grade only (A-F). (Lecture 3 hrs.)

546. Protein Structure and Function (3)

Prerequisites: Either CHEM 371B or CHEM 377B; and both CHEM 441A and CHEM 541 with the grade of "C" or better; or consent of instructor.
Principles of protein structure, folding, and function. Includes techniques used for the production, isolation and characterization of proteins.
Letter grade only (A-F). (Lecture 3 hrs)

547. Biochemistry of Nucleic Acids (3)

Prerequisites: CHEM 441B, CHEM 541 with the grade of "C" or better; or consent of instructor.
Gene expression with emphasis on regulatory mechanisms. Analytical techniques for isolation, purification, and characterization of nucleic acids.
Letter grade only (A-F). (Lecture 3 hrs.)

548. Cell Membranes (3)

Prerequisites: BIOL 340, BIOL 370, CHEM 441A, CHEM 541 with the grade of "C" or better; or consent of instructor.
Examination of modern membrane biochemistry. May include membrane structure and transport, phospholipids sorting, vesicular transport, membrane coat protein structure and function, and membrane-dependent signal transduction.
Letter grade only (A-F). (Lecture 3 hrs.)

549. Biochemistry of Lipids and Lipoproteins (3)

Prerequisites: BIOL 340, CHEM 441B, CHEM 541 all with the grade of "C" or better; or consent of instructor.
Current topics on the biochemistry of lipids and lipoproteins in health and disease. Lipid absorption, synthesis and transport; Cellular uptake of lipoproteins, lipid storage and mobilization; lipid signaling; cellular lipid efflux.
Letter grade only (A-F). (Lecture 3 hrs)

552. Selected Topics in Analytical Chemistry (3)

Prerequisite: CHEM 451 or consent of instructor.
Including electrochemical measurements, chromatographic techniques, spectroscopic techniques, radiochemical analysis and basic electronic components of instrumentation. Emphasizing the chemical principles involved, utility and limitations of each method. Includes trace analysis of water and air.
Letter grade only (A-F). May be repeated to a maximum of 6 units with different topics. Topics announced in the Schedule of Classes. (Lecture 3 hrs.)

553. Fundamentals of Electroanalytical Chemistry (3)

In-depth description of electrochemical processes and research techniques. Voltammteric, potentiometric, and impedance methods. Scanning probe techniques. Analysis of current research literature related to electroanalytical chemistry and surface science.
Letter grade only (A-F). (Lecture 3 hrs.)

572. Advanced Physical Chemistry (3)

Prerequisite: CHEM 371B or consent of instructor.
Special topics in physical chemistry.
May be repeated to a maximum of 6 units with different topics. Letter grade only (A-F). (Lecture 3 hrs.)

573. Molecular Spectroscopy (3)

Prerequisite: CHEM 371B or consent of instructor.
The interaction of electromagnetic radiation with atoms and molecules. Symmetry properties of molecules and the Hamiltonian. Angular momentum and the spectra of atoms and molecules. Pure rotational, vibrational, Raman, and electronic spectra of molecules. Understanding and predicting molecular spectra.
Letter grade only (A-F). (Lecture 3 hrs.)

574. Kinetics and Dynamics (3)

Prerequisite: CHEM 371A or consent of instructor.
Reaction rates for chemical systems; dependence on concentration and temperature. Derivation of the mechanisms of chemical reactions. Kinetic theory and analysis of experimental results for different systems. Dynamics of chemical reactions; transition state theory, potential-energy surfaces, and reaction pathways.
Letter grade only (A-F). (Lecture 3 hrs.)

580./480. Biomolecular Modeling and Simulation (3)

Prerequisites: CHEM 220A; MATH 123 (may be taken concurrently); PHYS 100B or PHYS 152, all with a grade of "C" or better.
The study of biomolecular phenomena using computer-based modeling and simulation techniques with varying degrees of resolution, including development and validity of molecular models.
Letter grade only (A-F). (Lecture 3 hrs.)

581. Biological Performance of Materials (3)

Advance studies of the chemical and mechanical interactions between materials used in medical devices and implants and living organisms. The course content includes materials response to biological system and host response to biomaterials.
Letter grade only (A-F). (Lecture 3 hrs.)

595A. Colloquium in Biochemistry (1)

595B. Colloquium in Organic Chemistry (1)

595C. Colloquium in Analytical, Physical and Inorganic Chemistry (1)

Prerequisite: Graduate standing or consent of instructor.
Discussion of advances as reported in recent literature. Provides experience in library use, organization, presentation, and critical evaluation of the chemical literature.
May be repeated to a maximum of 3 units (not more than a total of 3 units may be earned in any combination of CHEM 595 courses). Letter grade only (A-F). (Seminar 1 hr.)

660. Seminar in Chemistry (1)

Weekly meetings for presentation and discussion of advanced work in special fields including original research by faculty and graduate students.
Credit/No Credit grading only. (Seminar 1 hr.) May be repeated to a maximum of 3 units.

695. Directed Reading (1)

Survey of information in chemical literature on a current research topic, under direction of a faculty member. Written report prepared from these readings.
Letter grade only (A-F).

697. Directed Research (1-6)

Prerequisite: Arrangement with instructor.
Laboratory work supervised on an individual basis. A written report will be required.
Letter grade only (A-F). May be repeated to a maximum of 3 units.

697C. Directed Research (1-3)

Prerequisite: Arrangement with Instructor
Continuation of laboratory work supervised on an individual basis. A written report will be required.
Credit/No Credit grading only. May be repeated to a maximum of 3 units.

698. Thesis (1-6)

Prerequisites: Advancement to candidacy for M.S. in Chemistry or M.S. in Biochemistry and arrangement with instructor.
Planning, preparation and completion of a thesis in chemistry or biochemistry.
Letter grade only (A-F).


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